Cartilage-Surgery

Great Results for Joint Pain and Injury

Arthrosamid

Overview

Arthrosamid is an innovative injectable hydrogel (97.5% water, 2.5% cross-linked polyacrylamide) for knee osteoarthritis, offering sustained pain relief and improved joint function as a long-term, non-absorbable therapy.
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Mechanism of Action

Arthrosamid provides physical cushioning and lubrication within the joint. Recent research suggests it also produces an anti-inflammatory effect by upregulating IL1-RA in joint fluid, which helps block pain and swelling pathways.

Efficacy

Clinical studies have demonstrated significant improvements in pain, function, and quality of life for at least 12 months. WOMAC scores improved markedly from baseline to 12 months (from 45.7 to 21.9), with a 76% response rate at 6 months.

Safety and Side Effects

Most side effects are mild and transient, including arthralgia (joint pain) and swelling. Arthrosamid does not cause joint damage and is considered safe for longer-term use.
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Ideal for patients who:

  • Have osteoarthritis knee pain
  • Want to avoid surgery
  • Didn’t respond to steroid or hyaluronic injections